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                                                <h1 class="b">All-on-4®治疗概念</h1>
                                                <p>采用微创解决方案，具有固定的全弓形修复体，可提高患者满意度</p>
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                                                                        <p>In 1998 Dr. Paulo Malo successfully treated the first patient with the All-on-4<sup>®</sup>&nbsp;treatment concept. Since then hundreds of thousands of patients have been treated with this concept using Nobel Biocare implants.</p>
                                                                        <p>The All-on-4<sup>®</sup>&nbsp;treatment concept is the best solution for full-arch treatment using tilted implants. But only when Nobel Biocare products are combined. Many have tried to mirror this groundbreaking concept, but only we have the scientifically documented success to back it up.&nbsp;</p>
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                                                                                                        <h3 class="headline">
                                                                                                        What is the All-on-4® treatment concept?
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                                                                                                                                                <p>
                                                                                                                                                        The All-on-4<sup>®</sup>
                                                                                                                                                        &nbsp;treatment concept is a cost-efficient, graftless solution that provides
                                                                                                                                                        patients with a fixed full-arch prosthesis on the day of surgery.&nbsp;
                                                                                                                                                </p>
                                                                                                                                                <p>Characteristics include:</p>
                                                                                                                                                <ul>
                                                                                                                                                        <li>
                                                                                                                                                        <b>
                                                                                                                                                                Full-arch rehabilitation with only four implants&nbsp;
                                                                                                                                                                <br>
                                                                                                                                                        </b>
                                                                                                                                                        Two straight anterior implants and two implants tilted up to 45º in the
                                                                                                                                                        posterior
                                                                                                                                                        </li>
                                                                                                                                                        <li>
                                                                                                                                                        <b>
                                                                                                                                                                Immediate Function
                                                                                                                                                        </b>
                                                                                                                                                        &nbsp;(fixed provisional bridge)
                                                                                                                                                        <br>
                                                                                                                                                        For patients meeting criteria for immediate loading of implants
                                                                                                                                                        </li>
                                                                                                                                                        <li>
                                                                                                                                                        <b>
                                                                                                                                                                Graftless procedure
                                                                                                                                                                <br>
                                                                                                                                                        </b>
                                                                                                                                                        Bone grafting is avoided by tilting the posterior implants, utilizing
                                                                                                                                                        available bone
                                                                                                                                                        </li>
                                                                                                                                                </ul>
                                                                                                                                                <p>
                                                                                                                                                        <b>
                                                                                                                                                        ►&nbsp;
                                                                                                                                                        </b>
                                                                                                                                                        <a href="http://info.nobelbiocare.com/int/en/all-on-4-ebook" target="_blank">
                                                                                                                                                        Download e-book:&nbsp;How you can start with the All-on-4
                                                                                                                                                        <sup>®</sup>
                                                                                                                                                        &nbsp;treatment concept
                                                                                                                                                        </a>
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                                                                                                                                <h3>
                                                                                                                                        Why 98% of patients would recommend the All-on-4
                                                                                                                                        <sup>®</sup>
                                                                                                                                        treatment concept
                                                                                                                                        <sup>
                                                                                                                                        <a href="#footnote-1" class="js-media-lightbox" data-media-lightbox-type="reference">1</a>
                                                                                                                                        </sup>
                                                                                                                                </h3>
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                                                                                                                                                <p><b>Rapid improvement in quality of life</b></p>
                                                                                                                                                <p>
                                                                                                                                                        A fixed full-arch prosthesis on the day of
                                                                                                                                                        <br>
                                                                                                                                                        surgery quickly leads to improved patient satisfaction – with regards
                                                                                                                                                        to function,
                                                                                                                                                        <br>
                                                                                                                                                        esthetics, sense, speech and self-esteem.
                                                                                                                                                        <sup>
                                                                                                                                                        <a href="#footnote-2">2</a>
                                                                                                                                                        ,
                                                                                                                                                        <a href="#footnote-3">3</a>
                                                                                                                                                        </sup>
                                                                                                                                                </p>
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                                                                                                                                        <div class="mod mod-media-lightbox">
                                                                                                                                                <div class="content rich">
                                                                                                                                                <p><b>Shorter treatment times</b></p>
                                                                                                                                                <p>
                                                                                                                                                        Tilting of the posterior implants avoids the
                                                                                                                                                        <br>
                                                                                                                                                        need for time-consuming bone grafting procedures, while immediate loading
                                                                                                                                                        <br>
                                                                                                                                                        shortens time-to-teeth.
                                                                                                                                                        <sup>
                                                                                                                                                        <a href="#footnote-3" >3</a>
                                                                                                                                                        </sup>
                                                                                                                                                </p>
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                                                                                                                                                <p>
                                                                                                                                                        <b>
                                                                                                                                                        Lower costs
                                                                                                                                                        </b>
                                                                                                                                                </p>
                                                                                                                                                <p>
                                                                                                                                                        The concept is the least costly in comparison with conventional implant
                                                                                                                                                        treatment modalities of the edentulous and soon-to-be edentulous jaw.
                                                                                                                                                        <sup>
                                                                                                                                                        <a href="#footnote-3">3</a>
                                                                                                                                                        </sup>
                                                                                                                                                </p>
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                                                                                                        <h3 class="headline">Indications<i class="icon-arrow-down"></i></h3>
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                                                                                                                                        <h3>Patients with terminal dentition</h3>
                                                                                                                                        <p>
                                                                                                                                                A significant number of cases treated with the All-on-4
                                                                                                                                                <sup>®</sup>
                                                                                                                                                &nbsp;treatment concept are patients with failing dentition.
                                                                                                                                        </p>
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                                                                                                        <div class="textimage">
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                                                                                                                                <img alt="Example of a patient with terminal dentition eligible for the All-on-4® treatment concept" title="" src="images/all-on-4-pic-3.jpg">
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                                                                                                                                        <p style="text-align: center;">
                                                                                                                                                <i>
                                                                                                                                                Example of a patient with terminal dentition eligible for the All-on-4
                                                                                                                                                <sup>
                                                                                                                                                        ®
                                                                                                                                                </sup>
                                                                                                                                                treatment concept.
                                                                                                                                                </i>
                                                                                                                                        </p>
                                                                                                                                </div>
                                                                                                                        </div>
                                                                                                                </div>
                                                                                                        </div>
                                                                                                        <div class="textimage">
                                                                                                                <div class="mod mod-text-image skin-text-only clearfix">
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                                                                                                                                <div class="content rich">
                                                                                                                                <p>
                                                                                                                                        “Two thirds of patients we treat in our practice with full-arch restorations
                                                                                                                                        are soon-to-be edentulous patients.”
                                                                                                                                        <br>
                                                                                                                                        Dr. Wolfgang Bolz, Germany
                                                                                                                                </p>
                                                                                                                                <p>
                                                                                                                                        Patients with edentulism are also often eligible for the All-on-4
                                                                                                                                        <sup>
                                                                                                                                        ®
                                                                                                                                        </sup>
                                                                                                                                        &nbsp;treatment concept.&nbsp;A thorough evaluation of any patient is
                                                                                                                                        necessary in order to choose the right treatment and to establish a predictable
                                                                                                                                        treatment outcome. In our new e-book you will find four steps to help you
                                                                                                                                        identify the right patient and recommendations for treatment planning.
                                                                                                                                </p>
                                                                                                                                <p>
                                                                                                                                        ►
                                                                                                                                        <a href="http://info.nobelbiocare.com/int/en/all-on-4-ebook" target="_blank">
                                                                                                                                        Download e-book: How you can start with the All-on-4
                                                                                                                                        <sup>
                                                                                                                                                ®
                                                                                                                                        </sup>
                                                                                                                                        &nbsp;treatment concept
                                                                                                                                        </a>
                                                                                                                                </p>
                                                                                                                                </div>
                                                                                                                        </div>
                                                                                                                </div>
                                                                                                        </div>
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                                                                                       </section>
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                                                                                <div class="accordion-element-wrapper ">
                                                                                        <section class="accordion-element js-accordion-element ga-accordion" title="Milestones">
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                                                                                                        <h3 class="headline">Milestones<i class="icon-arrow-down"></i></h3>
                                                                                                </a>
                                                                                                <div class="accordion-content js-accordion-content js-accordion-slider-disabled"  style="display: none;">
                                                                                                        <div class="parsys">
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                                                                                                                <div class="mod mod-text-image  clearfix">
                                                                                                                        <div class="image">
                                                                                                                                <a href="#">
                                                                                                                                <img alt="Dr. Paulo Malo" title="Paulo-Malo_NobelSpeedy-user.jpg" src="images/all-on-4-pic-4.jpg">
                                                                                                                                </a>
                                                                                                                        </div>
                                                                                                                        <div class="mod mod-media-lightbox">
                                                                                                                                <div class="content rich">
                                                                                                                                        <ul>
                                                                                                                                                <li>
                                                                                                                                                        <b>1998</b> Dr. Paulo Malo treats the first patient using the All-on-4
                                                                                                                                                        <sup>®</sup>treatment concept
                                                                                                                                                </li>
                                                                                                                                                <li>
                                                                                                                                                        <b>2004</b>
                                                                                                                                                        &nbsp;Nobel Biocare launches the&nbsp;All-on-4
                                                                                                                                                        <sup>®</sup>treatment concept
                                                                                                                                                </li>
                                                                                                                                                <li>
                                                                                                                                                        <b>2011</b>
                                                                                                                                                        10 years follow-up in the mandible
                                                                                                                                                        <sup>
                                                                                                                                                                <a href="#footnote-3">3</a>
                                                                                                                                                        </sup>
                                                                                                                                                </li>
                                                                                                                                                <li>
                                                                                                                                                        <b>2012</b>
                                                                                                                                                        5 years follow-up in the maxilla
                                                                                                                                                        <sup>
                                                                                                                                                                <a href="#footnote-2">2</a>
                                                                                                                                                        </sup>
                                                                                                                                                </li>
                                                                                                                                                <li>
                                                                                                                                                        <b>2015</b>
                                                                                                                                                        &nbsp;34 clinical studies with 2000 patients
                                                                                                                                                </li>
                                                                                                                                                <li>
                                                                                                                                                        <b>2016</b>
                                                                                                                                                        &nbsp;More than 100 000 patients were treated with the All-on-4
                                                                                                                                                        <sup>®</sup>
                                                                                                                                                        treatment concept
                                                                                                                                                </li>
                                                                                                                                        </ul>
                                                                                                                                        <h6 style="font-family: tahoma, arial, helvetica, sans-serif; font-size: 12px;">
                                                                                                                                                &nbsp;
                                                                                                                                        </h6>
                                                                                                                                </div>
                                                                                                                        </div>
                                                                                                                </div>
                                                                                                        </div>
                                                                                                        </div>
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                                                                                        </section>
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                                                                                <div class="accordion-element-wrapper ">
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                                                                                                <a href="javascript:;" class="accordion-link js-accordion-link">
                                                                                                        <h3 class="headline">Science<i class="icon-arrow-down"></i></h3>
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                                                                                                                                                <div class="image">
                                                                                                                                                        <img alt="All-on-4® treatment concept - favorable bone and soft tissue parameters" title="" src="images/all-on-4-pic-5.jpg">
                                                                                                                                                </div>
                                                                                                                                        </div>
                                                                                                                                </div>
                                                                                                                        </div>
                                                                                                                        <div class="block_6 g-col g-col-2 column">
                                                                                                                                <div class="textimage">
                                                                                                                                        <div class="mod mod-text-image skin-text-only clearfix">
                                                                                                                                                <div class="mod mod-media-lightbox">
                                                                                                                                                        <div class="content rich">
                                                                                                                                                        <p>
                                                                                                                                                                <b>
                                                                                                                                                                Favorable bone and soft tissue parameters
                                                                                                                                                                </b>
                                                                                                                                                        </p>
                                                                                                                                                        <p>
                                                                                                                                                                Stable marginal bone levels
                                                                                                                                                                <sup>
                                                                                                                                                                <a href="#footnote-2">2</a>
                                                                                                                                                                ,
                                                                                                                                                                <a href="#footnote-3">3</a>
                                                                                                                                                        
                                                                                                                                                                &nbsp;
                                                                                                                                                                </sup>
                                                                                                                                                                and healthy soft tissue
                                                                                                                                                                
                                                                                                                                                                &nbsp;both for
                                                                                                                                                                <br>
                                                                                                                                                                tilted and axial implants.&nbsp;The graph shows results for the mandible,
                                                                                                                                                                but results for the maxilla are similar.
                                                                                                                                                        
                                                                                                                                                        </p>
                                                                                                                                                        </div>
                                                                                                                                                </div>
                                                                                                                                        </div>
                                                                                                                                </div>
                                                                                                                        </div>
                                                                                                                </div>
                                                                                                                
                                                                                                                <div class="g-row g-layout-responsive-50-50">
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                                                                                                                                <div class="textimage">
                                                                                                                                        <div class="mod mod-text-image skin-image-only clearfix">
                                                                                                                                                <div class="image">
                                                                                                                                                        <img alt="All-on-4® treatment concept - high patient satisfaction" title="" src="images/all-on-4-pic-6.jpg">
                                                                                                                                                </div>
                                                                                                                                        </div>
                                                                                                                                </div>
                                                                                                                        </div>
                                                                                                                        <div class="block_6 g-col g-col-2 column">
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                                                                                                                                                <div class="mod mod-media-lightbox">
                                                                                                                                                        <div class="content rich">
                                                                                                                                                        <p>
                                                                                                                                                                <b>
                                                                                                                                                                98% of patients would recommend this&nbsp;treatment
                                                                                                                                                                </b>
                                                                                                                                                        </p>
                                                                                                                                                        <p>
                                                                                                                                                                In one study, 95% of 250 patients were satisfied with their new teeth.
                                                                                                                                                                <br>
                                                                                                                                                                88% said they would definitely recommend similar treatment to friends
                                                                                                                                                                <br>
                                                                                                                                                                and colleagues and 10% would consider recommending it.
                                                                                                                                                                <sup>
                                                                                                                                                                <a href="#footnote-1">
                                                                                                                                                                        1
                                                                                                                                                                </a>
                                                                                                                                                                </sup>
                                                                                                                                                        </p>
                                                                                                                                                        </div>
                                                                                                                                                </div>
                                                                                                                                        </div>
                                                                                                                                </div>
                                                                                                                        </div>
                                                                                                                </div>
                                                                                                                
                                                                                                                <div class="g-row g-layout-responsive-50-50">
                                                                                                                        <div class="block_6 g-col g-col-1 column column-first">
                                                                                                                                <div class="textimage">
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                                                                                                                                                <div class="image">
                                                                                                                                                        <img alt="All-on-4® treatment concept - scientifically proven" title="" src="images/all-on-4-pic-7.jpg">
                                                                                                                                                </div>
                                                                                                                                        </div>
                                                                                                                                </div>
                                                                                                                        </div>
                                                                                                                        <div class="block_6 g-col g-col-2 column">
                                                                                                                                <div class="textimage">
                                                                                                                                        <div class="mod mod-text-image skin-text-only clearfix">
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                                                                                                                                                                <p>
                                                                                                                                                                        <b>
                                                                                                                                                                        The scientifically proven concept
                                                                                                                                                                        </b>
                                                                                                                                                                </p>
                                                                                                                                                                <ul>
                                                                                                                                                                        <li>
                                                                                                                                                                        34 clinical studies (clinical case reports excluded) with 2000 patients
                                                                                                                                                                        </li>
                                                                                                                                                                        <li>
                                                                                                                                                                        &gt; 9200 TiUnite implants
                                                                                                                                                                        </li>
                                                                                                                                                                        <li>
                                                                                                                                                                        Up to 10 years follow-up in the mandible and 5 years in the maxilla
                                                                                                                                                                        </li>
                                                                                                                                                                </ul>
                                                                                                                                                        </div>
                                                                                                                                                </div>
                                                                                                                                        </div>
                                                                                                                                </div>
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                                                                                                <strong>参考文献</strong>
                                                                                                <p id="footnote-1"></p>
                                                                                                <p>
                                                                                                        <b>1<sup>&nbsp;</sup></b>Arnhart C, Kielbassa
                                                                                                        AM, Martinez-de Fuentes R, Goldstein M, Jackowski
                                                                                                        J, Lorenzoni M, Maiorana C, Mericske-Stern
                                                                                                        R, Pozzi A, Rompen E, Sanz M, Strub JR. Comparison
                                                                                                        of variable-thread tapered implant designs
                                                                                                        to a standard tapered implant design after
                                                                                                        immediate loading. A 3-year multicenter randomized
                                                                                                        controlled trial. Eur J Oral Implant. 2012
                                                                                                        Summer; 5(2):123-36
                                                                                                </p>
                                                                                                <p>
                                                                                                        <a href="http://www.ncbi.nlm.nih.gov/pubmed/22866289" target="_blank">Read on PubMed</a>
                                                                                                </p>
                                                                                                <p id="footnote-2"></p>
                                                                                                <p>
                                                                                                        <b>2&nbsp;</b>McAllister BS, Cherry JE, Kolinski
                                                                                                        ML, Parrish KD, Pumphrey DW, Schroering RL.
                                                                                                        Two-year Evaluation of a Variable-Thread
                                                                                                        Tapered Implant in Extraction Sites with
                                                                                                        Immediate Temporization: A Multicenter Clinical
                                                                                                        Trial. Int J Oral Maxillofac Implants. 2012
                                                                                                        May-Jun; 27:611-18
                                                                                                </p>
                                                                                                <p>
                                                                                                        <a href="http://www.ncbi.nlm.nih.gov/pubmed/22616055" target="_blank">Read on PubMed</a>
                                                                                                </p>
                                                                                                <p id="footnote-3"></p>
                                                                                                <p><b>3&nbsp;</b>Cosyn J, De Bruyn H, Cleymaet R. Soft
                                                                                                        tissue preservation and pink aesthetics around
                                                                                                        single immediate implant restorations: A
                                                                                                        1-year prospective study. Clin Implant Dent
                                                                                                        Relat Res. 2012 [Epub ahead of print]</p>
                                                                                                <p><a href="http://www.ncbi.nlm.nih.gov/pubmed/22376232"
                                                                                                                target="_blank">Read on PubMed</a></p>
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